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Quick Details

  • CAS No.: 70-18-8
  • Other Names: Lyrica
  • MF: C63H88CoN14O14P
  • EINECS No.: 232-678-0
  • Place of Origin: Shaanxi, China (Mainland)
  • Type: Anesthetic Agents, Antipyretic Analgesics and NSAIDs, Central Nervous System Agents
  • Grade Standard: Medicine Grade
  • Usage: Animal Pharmaceuticals
  • Brand Name: Orient
  • Model Number: Top Grade
  • Purity: 99%min
  • Product Name: Pregabalin
  • Other Name: Lyrica
  • Appearance: White Powder
  • Grade: Phamaceutical Grade
  • Assay: 99.0~101.0%
  • Application: Pain Killer Powder,Anticonvulsant Drug
  • Shelf life: 24 Months
  • Certificate: ISO9001

Packaging & Delivery

Packaging Details Aluminum foil bag, paper drum, or as your requirement
Delivery Time within 7 working days after confirmation

Natural Pregabalin Powder For Pain Killer

Product Description

 

CAS No.:148553-50-8Other Names:PregabalinMF:C8H17NO2
EINECS No.:207-098-6Place of Origin: China (Mainland)Type:Auxiliaries and Other Medicinal Chemicals
Grade Standard:Medicine GradeBrand Name:orientModel Number:Enterprise standard
Purity:99%
Brief Introduction:

Pregabalin  is an anti-epileptic drug, also called an anticonvulsant. It works by slowing down impulses in the brain that cause seizures. Pregabalin also affects chemicals in the brain that send pain signals across the nervous system.

Pregabalin is used to control seizures and to treat fibromyalgia. It is also used to treat pain caused by nerve damage in people with diabetes (diabetic neuropathy), herpes zoster (post-herpetic neuralgia, or neuropathic pain associated with spinal cord injury.

Do NOT use pregabalin if:

  • you are allergic to any ingredient in pregabalin
  • Contact your doctor or health care provider right away if any of these apply to you.

Before using pregabalin:

Some medical conditions may interact with pregabalin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have heart problems (eg, congestive heart failure, irregular heartbeat), high blood pressure, muscle problems, diabetes, or bleeding problems or low platelets
  • if you have kidney problems or are on dialysis
  • if you have a history of mental or mood problems (eg, depression), suicidal thoughts or attempts, or alcohol or drug abuse
  • if you have a history of angioedema (swelling of the hands, face, lips, eyes, throat, or tongue; difficulty swallowing or breathing; or unusual hoarseness)
  • if you plan to father a child

Some MEDICINES MAY INTERACT with pregabalin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril) because the risk of angioedema may be increased
  • Benzodiazepines (eg, lorazepam) or narcotic pain medicines (eg, oxycodone) because the risk of drowsiness may be increased
  • Thiazolidinedione antidiabetic agents (eg, rosiglitazone) because the risk of weight gain or swelling of the hands and feet may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if pregabalin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Main Function:

 

1. Pharmacological efficacy: Pregabalin is a novel γ-aminobutyric acid (GABA) receptor agonist, can block the voltage-dependent calcium channels to reduce neurotransmitter release.

 2. The main clinical for the treatment of peripheral neuropathic pain as well as part of adjuvant treatment of focal seizures.

 3. Treatment of epilepsy in developing the most promising drug in a drug treatment better and more convenient administration. Can also be used to treat pain and anxiety.

How to use pregabalin:Use pregabalin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Pregabalin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get pregabalin refilled.
  • Take pregabalin by mouth with or without food.
  • Take pregabalin on a regular schedule to get the most benefit from it.
  • Taking pregabalin at the same time each day will help you remember to take it.
  • If you miss a dose of pregabalin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use pregabalin.

Important safety information:

  • Pregabalin may cause drowsiness, dizziness, blurred vision, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use pregabalin with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol while you are taking pregabalin.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are taking pregabalin; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Pregabalin may reduce the number of clot-forming cells (platelets) in your blood. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
  • Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.
  • Do not suddenly stop taking pregabalin or change your dose without checking with your doctor. If you stop taking pregabalin suddenly, you may have headaches, nausea, diarrhea, trouble sleeping, anxiety, or increased sweating. If you have epilepsy and you stop taking pregabalin suddenly, you may have seizures more often. If you need to stop taking pregabalin, your dose should be gradually reduced over a period of at least 1 week.
  • If you stop taking pregabalin for any reason, contact your doctor right away. Do not start taking it again unless your doctor tells you to. Discuss any questions or concerns with your doctor.
  • If you develop new or worsening seizures, contact your doctor right away.
  • Patients who take pregabalin may be at increased risk of suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Watch patients who take pregabalin closely. Contact the doctor at once if new, worsened, or sudden symptoms (eg, depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior) occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
  • Tell your doctor or dentist that you take pregabalin before you receive any medical or dental care, emergency care, or surgery.
  • Diabetes patients - Monitor your skin closely for any new or unusual sores while you take pregabalin.
  • In animal studies, birth defects were seen in the babies of male animals who were treated with pregabalin. It is not known if this may also occur in humans. If you are planning to father a child, discuss the possible risks with your doctor.
  • Use pregabalin with caution in the ELDERLY; they may be more sensitive to its effects.
  • Pregabalin should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using pregabalin while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking pregabalin.

Specifications:

Item 

Standard 

Result 

Appearance 

White or off white  crystalline powder

Off-White crystalline powder

Specific rotation 

+9.0~ +11.5°

+10.79°

PH

6.0~8.0

6.77

Loss on drying

≤0.5%

0.02%

Residue on ignition

≤0.1%

0.04%

Heavy metals 

≤0.002%

<0.002%

Assay (on dried basis)

≥98.5%

100.8%

R-pregabalin(HPLC)

≤0.5%

0.33%

 

Related substances

S-(+)-mandel ≤0.1%

0.3%

Unspecific individual impurity≤0.4%

0.08%

Total impurities≤1.0%

0.10%

Residual solvents 

isopropylketone≤3000ppm

tetrahydrofuran≤720ppm

585.0ppm

ND

Conclusion 

Comply with the  enterprise   standard

 

Side Effects of Pregabalin:

Get emergency medical help if you have any of these signs of an allergic reaction to Pregabalin : hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects while using Pregabalin :

  • muscle pain, weakness, or tenderness (especially if you also have a fever and feel tired);

  • vision problems;

  • easy bruising or bleeding; or

  • swelling in your hands or feet, rapid weight gain.

Packaging & Shipping

Packing:25kg/drum (25kg net weight,28kg gross weight; Packed in a cardboard-drum with two plastic-bags inside. Drum Size: 510mm high, 350mm diameter) ; 

1kg/bag (1kg net weight, 1.2kg gross weight, packed in an aluminum foil bag inside and paper carton outside ) or as per your request.

Storage:Storein cool & dry place. Do not freeze. Keepaway from strong light and heat.

Shelf life: two years when properly stored

 

Company Information

FAQ

Q1: Can i get some samples?

A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.

Q2: How to start orders or make payments?

A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal or Escrow(Alibaba).

Q3: How to confirm the Product Quality before placing orders?

A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.

Q4:What’s your MOQ?

A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.

Q5: How about delivery leadtime?

A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q6:Is there a discount?

A:Different quantity has different discount.

Q7: How do you treat quality complaint?

A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q8: How to contact us ?

A:You can chat with us by Trademanager,MSN&Skype Online. You can choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.

 

If you are interested in this product, Please click here and send me an Inquiry!

 

 

 

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Supplier's Trade Assurance Limit: US $44,000
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